ArrowBiome
A confident woman, fresh and carefree

Application · Body Odour · ArcherZyme®

Gold Award · Active Ingredient Category · in-cosmetics Asia 2025

The world’s first clinically validated lysin for body odour control.

ArcherZyme® is fast-acting: it is designed to address the factors that cause underarm odour while preserving the rest of the underarm microbiome. in-cosmetics Asia 2025 Gold Award winner.

Underarm odour is linked to specific bacteria.

Conventional deodorants either act broadly (alcohol, antimicrobials), block sweat (aluminium), or mask. ArcherZyme® is designed to address the bacteria associated with underarm odour, including S. hominis, while leaving the rest of the skin’s microbiome in balance.

ArcherZyme® · body odour
Good community: undisturbed S. hominis ArcherZyme protein

ArcherZyme® is a phage-derived enzyme that recognises and selectively acts on bacteria associated with underarm odour, such as S. hominis, while leaving the rest of the skin community undisturbed.

Fast-acting, clinically validated

Fast-acting, with odour still reduced 24 hours after a single use.

ArcherZyme® is built for speed. In the lab, it measurably reduces odour-associated bacteria within 10 minutes of application. In the clinical study, the first odour reading was taken at 2 hours, where the treated side was already ~61% fresher, and we expect future studies with earlier measurement points to show the benefit sooner still.

~0%

odour reduction by the first clinical reading at 2 hours, vs the untreated control underarm

~0%

odour reduction still measured at 24 hours (control: +5.1%)

0%

would buy an ArcherZyme® product that promised better long-term odour control

0%

agreed body odour was reduced over a week of daily use

Lab: odour-associated bacteria reduced within 10 minutes (in vitro)
100% agreed odour was controlled for 2–6h (questionnaire during a week of home use)
88.9% agreed its odour-reduction performance was “excellent”
S. hominis reduced more than S. epidermidis; no significant change in Cutibacteria or Corynebacteria

Clinical study: n=27, randomised split-axilla design (one underarm treated, one untreated control), single supervised application + one week daily home use. Odour scored by a 6-person sniffer panel (0–10 scale) at 0h, 2h, 8h and 24h, plus qPCR microbiome analysis. The 2-hour point was the first measurement; earlier time points were not assessed in this study. 10-minute activity is from in vitro testing. Published as van Steensel et al., JEADV Clinical Practice, 2026 (doi.org/10.1002/jvc2.70384). Panel size, measurement schedule and questionnaire percentages are from the full clinical study report, available on request.

For formulators

For formulators.

Evaluation samples are available for purchase, typically after an introductory call, never a free giveaway. Once you have a sample in hand, our team works alongside you, at no charge, to turn it into a successful formulation.

Use level (add rate)1% w/w of the ArcherZyme® ingredient
Active in finished product0.01%
AppearanceWhite, odourless freeze-dried powder
FormatsRoll-on, spray, body oil, lotion
ProcessingCold-process friendly
Stability24 months at 25°C (testing ongoing)
SafetyNon-irritant (IS 4011:2018; OECD 439); aluminium-free
IPMIT-licensed WO2022104171

Formulating with our actives

Built to drop into your formula.

Both actives are protein-based, so formulation friendliness comes down to protecting the protein. Below is the practical guidance our team shares with formulators. Full compatibility tables and stability support come with a sample.

Two numbers, and why they differ

Use level (what you add)

1% w/w

of the ArcherZyme® ingredient

Active in finished product

0.01%

at the 1% use level

There are two figures worth keeping distinct. The use level is how much of our ready-to-use ingredient you add to your formula: 1% w/w for both ArcherZyme® and SmartArrow®. The active level is how much engineered active that translates to in the finished product: 0.01% for ArcherZyme® and ~0.03% (recommended) for SmartArrow®. In short: you add 1% of our ingredient, and the active does its work at a fraction of a percent. Our team will confirm the exact use level for your specific format.

Recommended pH 5.5–8.5Add cold in the final phase at ≤30–40°C; gentle mixing to avoid shear and foaming.

Plays well with

  • Base & solvents: Buffered water, propanediol, propylene glycol
  • Humectants: Glycerol, trehalose, dextran, amino acids
  • Gelling agents: Carbomer 940, HEC, HPMC, chitosan
  • Thickeners: Cellulose gum, xanthan gum (minimal)
  • Surfactants: Polysorbate 20/60/80, poloxamer 184/188, decyl/coco-glucoside (minimal)
  • Oils: Caprylic/capric triglyceride, squalane, dimethicone, mineral oil
  • Stabilisers: Trehalose, tocopherol, sodium ascorbyl phosphate (EDTA: SmartArrow® only)

Best avoided

  • Alcohols: Ethanol, isopropanol: denature proteins even at low levels
  • Strong ionic surfactants: SLS, SLES (CAPB only if validated): denaturing
  • Reactive aldehydes: Citral, cinnamaldehyde, benzaldehyde: react with protein
  • Reducing sugars: Glucose, fructose, lactose: Maillard reaction over time
  • Alkaline soap systems: pH >9 irreversibly unfolds protein
  • Inorganic thickeners: Polyphosphates, clays: can bind/adsorb protein
Reference formulationBody oil (anhydrous)
Caprylic/capric triglycerideCarrier oil80–85% w/w
Jojoba seed oilNatural oil10% w/w
Silica dimethyl silylateRheology modifier5% w/w
ArcherZyme®Active1% w/w (→ 0.01% active in finished product)

Reference formulation by Chaks Cosmetic Design & Services Pte. Ltd. Illustrative only, not final or exhaustive. Guidance is based on formulation principles and compatibility observations for enzyme-based actives. Confirm stability in your intended product matrix; our team will support you.

Claim directions

Marketing claims your brand team can build on.

Performance

  • Clinically evaluated all-day freshness
  • From application to action in minutes (in vitro)
  • 100% body odour control after one use

Safety

  • Zero irritation, dermatologically tested
  • Microbiome-safe innovation
  • Aluminium-free formula

Sustainability

  • Micro-level active (0.01% in finished product), macro performance
  • Precision-fermentation derived
  • Energy-efficient production

Positioning

  • Advanced molecular engineering
  • High-performance enzymatic technology
  • Premium biotech for daily confidence

Claim directions are starting points for partner marketing. Final claims must be substantiated and reviewed for the target market and product format.